If you are running MOVEit Automation as a service, and you want to access remote (or mapped) Windows file systems, you must run that service as a specific Windows administrator, not as LocalSystem. New installations of MOVEit Automation are configured this way.
Note: Early installations of MOVEit Automation set up the MOVEit Automation service to run as LocalSystem. For instructions on how to convert from LocalSystem to a specific account, see Converting From MOVEit Automation as a LocalSystem Service.
If you want to authenticate MOVEit Automation Admin (and MOVEit Automation API) users to a Windows domain (or Active Directory), you might need to run MOVEit Automation under a domain user account that is also an administrator on the local MOVEit Automation machine. If you do not, you might see "RPC Server is unavailable" errors when your domain users attempt to authenticate to MOVEit Automation.
Preferred: Run MOVEit Automation as a domain user with local administrative permissions.
Not recommended: Run MOVEit Automation as a full domain administrator.