If you are running MOVEit Central as a service, you must run that service as a specific Windows administrator rather than as "LocalSystem" if you want to access remote (or mapped) Windows file systems. Fortunately, this is how new installations of MOVEit Central are configured.
If you wish to authenticate MOVEit Central Admin (and MOVEit Central API) users to a Windows domain (or Active Directory), you may need to run MOVEit Central under a domain user account that is also an administrator on the local MOVEit Central machine. (If you do not, you may see "RPC Server is unavailable" errors when your domain users attempt to authenticate to MOVEit Central.) It is rarely a good idea to run MOVEit Central as a full domain administrator; running as a domain user with local administrative privileges is preferred.
Converting From MOVEit Central as a LocalSystem Service
If you are running the MOVEit Central service as LocalSystem and you want to switch this to a specific administrator account, please follow the following procedure. Go to Administrative Tools / Services. Right-click on MOVEit Central and choose Properties. Choose the Log On tab. You will see that the Local System account is selected. Choose "This account" and select a local administrator account (for which you know the password). Then choose OK to change the user under which MOVEit Central runs. This step is necessary because Windows will not allow services to access network shares if they are running under the local system account.
The account you choose must have the Act as part of the operating system right. To configure this, go to Administrative Tools / Local Security Policy. Expand the Local Policies tree and choose User Rights Assignment. Double-click on Act as part of the operating system. Choose the Add button on the resulting dialog, and add the user under which the service will be running.
The account you choose must also have full file/folder permission rights to the MOVEit Central "Program Files\MOVEit" folder and cache folder.